The Causes of Pancreatic Cancer

There are many causes of pancreatic cancer. This cancer is among the most deadly types of cancers. In most cases the body is badly damaged by the time this cancer is diagnosed. Being relatively resistant to treatment pancreatic cancer is normally cured through surgery. It has been very challenging to treat this type of cancer even with the advance in modern medicine. Over 90% of people diagnose with this cancer die from it. This is why it is crucial to know the pancreatic cancer causes so that we can prevent it from developing in our bodies. These causes have been determined through the study of cancer biology and human population based studies. This cancer comes about as a result of DNA mutations by one or more of the risk factors discussed here. Some of the pancreatic cancer causes can be avoided while others can’t.

Causes of pancreatic cancerCigarette smoking doubles the risk of one acquiring pancreatic cancer. It is considered to be the leading cause of pancreatic cancer. Cigarette smoking is a preventable pancreatic cancer cause and it is really sad that in every five cases of pancreatic cancer, one is caused by cigarette smoking. Studies also show that anyone who quits smoking greatly reduces his/her chance of getting pancreatic cancer.

Inflammation of the pancreas for a long time( a condition known as chronic pancreatitis) is also among causes of pancreatic cancer. This must be treated early to prevent it from causing pancreatic cancer. In most cases, inflammation of the pancreas is due to excessive intake of alcohol.

The Causes Of Pancreatic Cancer

Being of the male gender is a risk factor as far as pancreatic cancer is concerned. This cancer is more common in men than in women with the ratio 1.3: 1. This may be attributed to the fact that men smoke cigarette and consume alcohol more compared to women.

Diabetes is regarded as a cause and symptom of pancreatic cancer. Diabetes that develops in adulthood increases the chances of one acquiring pancreatic cancer.

As it is the case with all most if not all types of cancer, the chance of you getting pancreatic cancer increases as your age increases. It is estimated that over 80% of cases of pancreatic cancer is reported from people between ages of 60 and 80. Hence old age can be considered as one among the causes of pancreatic cancer.

The genetics also play a big role in the development of pancreatic cancer. One is more likely to get this cancer if their family has some history with it. This is because a child can inherit cancer syndrome from the parents.

Other factors that are considered as causes of pancreatic cancer include obesity and diet. The risk of pancreatic cancer is significantly increased when one is obese. Diets high in cholesterol, meats and nitrosamines increase the chances of one getting pancreatic cancer. Fructose which is a sweetener in soft drinks causes abnormal growth of the cells of the pancreas. Fruits and vegetable on the other hand reduce the risk. Helicobacter pylori infection and gingivitis can also lead to the development of pancreatic cancer and therefore is told to be one of the causes of pancreatic cancer.


Causes of pancreatic cancer, symptoms and tests needed for diagnostics

There are a quite a few causes of pancreatic cancer. The pancreas is one of the organs in the abdomen which creates the digestive insulin, juices and other hormones. The juices will flow by ducts in to the intestine. Mostly the pancreatic cancer takes place in these ducts only. The danger of growing pancreatic cancer is similar for women and men. This type of cancer is known as silent disease since it is hard to identify and symptoms do not generally seen till cancer has developed for certain time. Causes of pancreatic cancer are because of uncontrolled development of abnormal cells. If these cells develop and form a lump of cells, that is known as tumor. If the pancreatic tumor cells break away and enter in to the lymphatic system, they have the ability to spread the cancer. This process is known as metastasis and the areas where it has developed are known as metastases. The reason for the growth of cancer cells is not identified still now, but the studies shows that people with some risk factors will have chances to grow pancreatic cancer than other people. The other reasons for the causes of pancreatic cancer are age. The risk of this type of cancer rises with the age.

Causes of pancreatic cancer

Causes of pancreatic cancerMost of the people who are above 60 are likely to occur. Another cause of pancreatic cancer is those who have chronic pancreatitis may have a risk of getting this pancreatic cancer. It is also common among the people who have diabetes. Smoking, obesity and family are also one of the causes of pancreatic cancer. The symptoms which are seen are loss of appetite, nausea, weakness and weight loss. The diagnosis of this cancer needs that the doctor performs a full physical test that includes with lab tests. The doctor will ask the patients about the family medical history and the patient’s personal history. Along with the normal test like temperature, blood pressure, he will also ask the patient to take various tests such as urine test, blood test and stool tests. He may ask the patient to have a upper gastrointestinal test. The patient will be asked to drink barium liquid prior x-rays of the upper digestive system test.

Pancreatic Cancer CausesThis solution will display the outline of the pancreas on the x-rays. The others test that are needed are x-ray of the blood vessels, CT scans the images will be created by the computer and it will offer a full cross division picture of the pancreas. The transabdominal ultrasound method avail an instrument which sends the high frequently waves and it will be passes on the abdomen. The waves form the images on the screen because they reflect off the pancreas. ERCP is one type of special x-ray test of the bile duct. The patient will be given sedation and one tube will be passed down the throat of the patient, by stomach and in to intestine. Biopsy is also another procedure for the doctor to check whether the cancer is present. Doctors will also determine by having tissue sample test and after finding, they will give medicines and if needed, the doctors will also suggest for surgery. Stay away from activity what causes of pancreatic cancer.


Pancreatic Cancer Stages

As the title would suggest this article is going to discuss the different stages of pancreatic cancer, but before we can talk about pancreatic cancer stages we have to talk about what pancreatic cancer is and why it is so important to understand. It is estimated that in the United States of America in 2012 that there will be approximately 43,920 new cases of pancreatic cancer and 37,390 deaths from this deadly form of cancer.

Pancreatic cancer, also known as exocrine cancer is defined as a disease in which malignant(cancerous) cells are found in the pancreas. This type of cancer is so deadly mainly because it is usually symptomless in the early stages of the disease. It is not until the cancer has progressed to the more advanced stages that symptoms begin to manifest, and at this point the chances of survival are diminished.

Pancreatic cancer stages

Pancreatic cancer is staged based on the size of the tumor in the pancreas, and by how much it has metastasized(spread). There are five stages by which pancreatic cancer is staged, from zero to four.

Pancreatic cancer stages – Stage 0

Pancreatic Cancer StagesThe zero stage with pancreatic cancer is when abnormal cells are found within the tissue lining the pancreas organ. At this stage there is no cancer, however the abnormal cells may become cancerous in the future. Pancreatic cancer stage 0 is also sometimes referred to as carcinoma in situ.

Pancreatic cancer stages – Stage 1 (Size approx 1-2cm)

  • Stage 1 is when cancer has formed within the pancreas, and has not metastasized(spread). Stage 1 is divided into two sub stages referred to as stage 1A and stage 1 B.
  • Stage 1A: The size of the pancreatic tumor is 2 centimeters or less.
  • Stage 2B: The size is greater than 2 centimeters.

Pancreatic cancer stages – Stage 2 (size approx 2cm)

The second stage of pancreatic cancer is defined by the spread of the cancer to nearby tissues or organs, and in some cases spread to the lymphatic system. Similar to stage 1, stage 2 is also divided into 2 sub stages.

  • Stage 2A: Cancer has metastasized to nearby organs and tissues, but not to the lymphatic system.
  • Stage 2B: Cancer has metastasized to the lymphatic system and to nearby organs and tissues.

Pancreatic cancer stages – Stage 3 (size approx 4cm)

By the time the cancer has been staged as a stage 3 the cancer has metastasized to the blood vessels surrounding the pancreas, and possibly the lymphatic system.

Pancreatic cancer stages – Stage 4 (Size approx 5cm)

In this stage of the cancer the tumor could be any size. Also in this stage there is usually a great deal of spreading of the cancer to major organs such as the lungs and lymphatic system.

Symptoms Of Pancreatic CancerThe above mentioned pancreatic cancer stages are just that stages, and within each stage there is room for interpretation. There needs to be room for interpretation due to the fact that each cancer is different and does not neatly fit into pre-determined boxes or stages. So just remember that the pancreatic cancer stages system is a guideline for doctors and that one doctor may see a stage 2 while another doctor may see that same tumor as a stage 1.


Pancreatic cancer causes

Don’t risk your pancreas, stay away form these pancreatic cancer causes activities. Pancreas is an endocrine gland and a digestive organ that is present in the abdomen region. Its plays a major role in digestion by secreting pancreatic juices containing digestive enzymes and also responsible for secreting a few important hormones like insulin and glucagon. The digestive juices secreted flow into the intestine through ducts and this is where most pancreatic cancers occur. About one out of every 79 persons will develop a pancreatic cancer and it is stated that this has been the fourth most common fatal cancer around the globe.

Like all other cancers the pancreatic cancer will result in uncontrolled growth of abnormal cells which then will burst and spread the cancer throughout the body through blood. This ultimately leads to death unless proper treatment is provided in the initial stage itself.

Pancreatic Cancer Causes

Though the reason for development of cancer cells is not exactly known, the researchers have come up with a list of risk factors that make people more prone to pancreatic cancer. The risk factors are as follows,
• Age: This has been an unavoidable reason for cancer and the risk increases with increasing age. Mostly people above the age of 60 are more prone to the disease and researches say both men and women have equal chances of getting affected.
• Smoking: People who smoke cigarettes have three times more chances of having the cancer than the ones who don’t smoke and hence smoking is reported as the most significant risk factor. It is estimated that one third of the pancreatic cancer cases are caused due to smoking. Pancreatic cancer causes
• Diabetes: People affected by diabetes mellitus have higher risks.
• Diet is also a significant factor. Diet lacking fruits and green vegetables and diet with high amount of red meat and sugar may result in cancer.
• Obesity: Obese persons have higher risks of getting the cancer.
• Heredity: When one of the parents have had pancreatic cancer then the chances for their children having the same is three times greater than others.
• Chronic pancreatitis also increases the chances of having cancer.
• People affected by Helicobacter pylori and Gingivitis are also prone to the disease.
It remains a controversy whether consumption of alcohol leads to pancreatic cancer or not. Although many studies have proved that alcohol intake is not associated with pancreatic cancer, excessive alcohol consumption leads to chronic pancreatitis which in turn results in cancer. According to researchers about 30g of alcohol a day will not increase the risks of having pancreatic cancer.

Symptoms:Pancreatic cancer causes
Pancreatic cancer is also called as ‘silent killer’ because the disease often fails to show symptoms in the early stages. In the later stages the common symptoms noted are pain in the upper abdomen, loss of appetite, loss of weight, painless jaundice and increased sugar level.

The treatment of pancreatic cancer varies in procedure based on its stage and remains very effective only in the earlier stages. Mostly it is treated by a minimal invasive laparoscopy surgery and involves removal of cancer cells. It can also be treated by chemotherapy.
Prevention is found to be the best way to stay away from pancreatic cancer. So stay away from these pancreatic cancer causes.

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